In 1975 a new NGO named Presbyterian Fellowship in Bangladesh (PFB) set its foot in the post-liberation era of Bangladesh. It started working by providing medical services and arranging relief programs as representative of the Presbyterian Church of USA (PCUSA). In those initial days the well-known American Presbyterian physician Dr. Herbert Codington came to organize and support this work in Bangladesh; he was mainly confined with his programs at Ershad Nagar near Tongi.

But in 1992 the medical work extended from there to a village called Karamtola in Pubail Union in Gazipur district and eventually a new project called Community Health and Development Program-Karamtola (CHDP-K) was started there. Fortunately for CHDP-K this had been a fixed project site, about 28 kilometers from Dhaka. Korean Overseas Medical Mission Society (KOMMS) and Church of Bangladesh (COB) also joined their hands, as partners, with PCUSA. People had a huge acceptance of their services. And consequently it was popularly called CHDP-K clinic at that time.

And the days started moving on. This very modest referral clinic at Karamtola started gradually growing in size, in extent and quality of its services, which today has become the Karamtola Community Hospital (KCH).

From the very beginning, this organization attached its priorities on supporting the poor underprivileged and vulnerable people of Bangladesh. A Community Nursing School was started in 2007. Karamtola Eye Service Project (KESP) emerged side by side with it in 2010. With a few more new projects like Primary Health Care Project, Dhaka Aviation Consortium Clinic, Peniel School, etc emerging later on, Presbyterian Fellowship in Bangladesh (PFB) became a real community focused centre in course of time.

At present this organization primarily covers a total population of 5,263,474 in Gazipur district and also works in the nearby areas of Dhaka, targeting some special groups of beneficiaries (As per population census of 2022).